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yhdR [2018-09-06 18:28:54]
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yhdR [2018-09-06 18:28:54]

similar to aspartate aminotransferase
locus
BSU09570
pI
5.01
mw
43.73 kDa
protein length
393 aa Sequence Blast
gene length
1179 bp Sequence Blast
function
unknown
product
unknown
essential
no
ec
2.6.1.1
synonyms

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]
  • Gene

    Coordinates
    1,034,046 → 1,035,227

    The protein

    Catalyzed reaction/ biological activity

  • L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate (according to Swiss-Prot)
  • Protein family

  • [SW|class-I pyridoxal-phosphate-dependent aminotransferase family] (according to Swiss-Prot)
  • [SW|Cofactors]

  • PLP
  • Structure

  • [PDB|3ELE] (from Eubacterium rectale, 34% identity)
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • Additional information

  • The gene is annotated in KEGG as aspartate aminotransferase EC 2.6.1.1. In MetaCyc the protein is marked as “similar to aspartate aminotransferase”. No EC annotation is available in Swiss-Prot. No literature/experimental evidence supporting the annotation is availablavailable. [Pubmed|19935659]
  • Expression and Regulation

    Operons

    genes
    [gene|8F7432F7EF0F767C6000D553A3ACE29FBA2EDCEE|yhdR]
    description
    [Pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-B485 (yhdR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1484 NBRP B. subtilis, Japan]
  • BKE09570 (Δ[gene|8F7432F7EF0F767C6000D553A3ACE29FBA2EDCEE|yhdR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE09570 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTGTCCCTTCCGCATAT, downstream forward: _UP4_TAAGAAGGCAAAGAAAAGAA
  • BKK09570 (Δ[gene|8F7432F7EF0F767C6000D553A3ACE29FBA2EDCEE|yhdR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK09570 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTGTCCCTTCCGCATAT, downstream forward: _UP4_TAAGAAGGCAAAGAAAAGAA